98年第1學期-4320 生物物理學 課程資訊

評分方式

評分項目	配分比例	說明
書面報告	60

教育目標

啟發生科系學生對物理學的興趣，介紹生物物理學基本原理與未來研究發展的趨勢。

課程概述

本課程介紹物理學在生物學上的運用，例如研究蜘蛛如何站立在天花板上附著機制，或是水黽如何在水面上行走時的力學。課程以深入淺出的方式，將物理學研究自然現象的方法學與理論架構，運用在生命科學的研究上。

基本資料

選修課，學分數：2-0
上課時間：一/6,7,8[LS124]
修課班級：生科碩博
修課年級：年級以上
選課備註：

參考書目

各主題的參考文獻如下：
Topic1 Dimensional analysis and Fermi problem
P. W. Bridgman, Dimensional Analysis (Yale University Press, 1922; Reprinted: Kessinger Pub., 2008).
L. Weinstein and J. A. Adam, Guesstimation: Solving the Worlds Problems on the Back of a Cocktail Napkin (Princeton University Press, 2008).
Topic2 Biomechanics: Fluid Mechanics
M. W. Denny, Air and Water (Princeton University Press, 1993). (Chapters 2, 4, 5, 7)
Topic3 Biomechanics: Biological materials and structures
S. Vogel, Comparative Biomechanics: Lifes Physical World (Princeton University Press, 2003). (Chapters 15-16, 18-20)
Topic4 Locomotion and scaling in biology
K. Schmidt-Nielsen, Animal Physiology: Adaptation and Environment, 5th ed. (Cambridge University Press, 1997). (Chapter 10)
S. Vogel, Comparative Biomechanics: Lifes Physical World (Princeton University Press, 2003). (Chapter 3)
Topic5 Biological pattern formation
P. Ball, Shapes Natures Patterns: a tapestry in three parts (Oxford, 2009). (In particular, Chapter 4: Written on the Body)
Topics6-7 Physics of bio-sensing
M. W. Denny, M. W. Denny, Air and Water (Princeton University Press, 1993). (Chapters 10-11)
Topics8-9 Nano-biomimetics
(1)Pete Vukusic and J. Roy Sambles. Photonic structures in biology. Nature 424-852 (2003).
(2)Bharat Bhushan. Biomimetics: lessons from nature–an overview. Philosophical Transactions of The Royal Society A 367-1445 (2009).
(3)Markus Heim, David Keerl, Thomas Scheibel. Spider Silk: From Soluble Protein to Extraordinary Fiber. Angewandte Chemie InternationalEdition, Articles online in advance of print.
(4)Philip Ball. Natural strategies for the molecular engineer, Nanotechnology 13-R15 (2002).
Topic10 Applications of microscopy to biophysical research
To be determined.